Topiramate (Topamax) Effective against severe myoclonic epilepsy in infancy. For children over 2 years of age. Recommended in partial and generalised seizures. Possible side effects: Pins and needles in hands and feet and loss of weight, headache, drowsiness. Increased risk of kidney stones. Slowing of mental performance and language may occur but minimised if dose started low and increased slowly. Cases of eye reactions have rarely been associated with topiramate occurring within one month of commencement of treatment.